Addy Osmani's post may be over 2 years old, but it still is incredibly insightful for helping new Backbone developers think through architecture decisions.
Ok, ok, ARGUABLY the book on developing Backbone.js applications... Written by Addy Osmani, this is one of my staple resources these days, along with his todoMVC example.
I'm going to be going back to this regularly for a refresher. Learning best practices when building responsive sites is mostly about performance and efficiency. App development best practices must start with security.